Web Reference: Blood, the journal of the American Society of Hematology, publishes cutting-edge research and clinical advances in hematology and oncology. 2 days ago · A Dried Platelet-Derived Biologic for Blood-Brain Barrier Repair and Hemorrhage Control Following TBI in Mice Alpa Trivedi, Byron Y Miyazawa, Haoqian Zhang, Longhui Qiu, Daniel Potter, Austin William Edwards, Lindsay Vivona, Maximillian Lin, Callie Keane, Huimin Geng, Simon J Cleary, Alison Nair, Michael M Fitzpatrick, Mark R. Looney, Shibani Pati Nov 28, 2024 · Preclinical data demonstrate that Janus kinase 2/signal transducer and activator of transcription (JAK2/STAT3) activity is integral to differentiation of alloreactive T cells, suggesting that JAK2 inhibition could prevent the development of graft-versus-host disease (GVHD). In a multicenter phase 2 trial, Pidala et al tested this hypothesis, reporting that a GVHD prevention regimen of ...
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