Web Reference: Mar 26, 2025 · Sitting for long periods — such as in front of the TV or at a desk — seems to raise the risk of death from heart disease and cancer. May 25, 2023 · If your work involves sitting at a desk, discomfort doesn't have to be part of the job. You may be able to avoid some of the health problems associated with seated work, such as neck and back pain and sore wrists and shoulders, by using proper office ergonomics. Chair height, equipment spacing and desk posture all make a difference. Leg pain can have many causes, but your description of aching after prolonged standing or sitting suggests a possible buildup of fluid in the leg veins (chronic venous disease, venous insufficiency). Chronic venous disease occurs when the valves in your leg veins don't work properly to keep blood moving efficiently from your legs to your heart.
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